It's like hot chick kryptonite. [post-album postid="224275" item="1"]This morning we have a new trailer for Will Reiser's autobiographical 50/50 that focuses more on the comedic and less on the film's bummerific aspects. This shorter look leans more heavily on Seth Rogen to make light of Joseph Gordon-Levitt's cancer like any good friend would. Though as evidenced here, using cancer to pick up chicks isn't as foolproof as it sounds. It's cancer. Not a puppy. 50/50 opens in theaters on September 30th and also stars Anna Kendrick, Bryce Dallas Howard, Phillip Baker Hall, and Angelica Houston.