Splice is the latest mistake from the sci-fi horror genre, having no thrills or logic in its pseudo-hipster science.
A major disappointment comes from its talented cast of Adrien Brody and Sarah Polley, as scientist power couple Clive and Elsa. Sadly, they spend more time dressing up in hipster chic than finding logic in creating their newest creation: a protein-human hybrid named Dren (played with bizarre eroticism by Delphine Chaneac).
Cult director Vicenzo Natali of Cube and Nothing, explains that the movie is about the cycle of life that Dren takes from conception by her half-witted scientific parental unit, who wants to keep reminding each other that it’s for the betterment of mankind—a warning to all audiences that they will create absolute horror, as Dren grows into fetal form of a hormonal teenager and then finally taking a sexual metamorphism into a grown male monster, which the regular movie audience might find shocking, but for sci-horror fans it's simply the same old song and dance number of violence and gore.
Director Natali seems to be heavily inspired by The Fly and Dead Ringers, both of which are by his fellow Canadian director David Croenberg, who is known for his hybrid style of sci-fi goo and eroticism that creates a special kind of biological horror movies. With Splice we have a movie that knows the words, but not the music.
What should be noted about Splice are the performances and especially details of Chaneac's Dren, because we have this amazing physical and verbal performance from the unknown actress as she creates this Frankenstein-type character ambit the most idiotic scientific couple.
The movie has a promising start from the slick and gooey opening credit roll, but once Brody and Polly find themselves taking care of their hybrid child, the movie amounts to a series of ridiculous events helped with a badly acted supporting cast, ending in a climax that is as sterile as a petri dish.