Pack it up, Apatow. You had a good run but there's a new wave of comedy washing into Tinseltown. So pack up your shit.

According to the NY Post, popular yucksters Robert De Niro and Sean Penn are teaming up for The Comedian. De Niro stars as an insult comic in the vain of Don Rickles in the film scripted by Art Linson and Jeffrey Ross. Sean Penn is in talks to direct, not Martin Scorsese as previously reported.

I'm sure this will be the laugh-out loud hit of the year. Actually, all years. With the super-bubbly Sean Penn and Robert De Niro on board, how could it not be? Throw in a role for funnyman Russell Crowe and we may all need crutches from over-slapped knees.