The best "Mean Girls" quotes comes from a variety of characters featured in the 2004 comedy. The movie revolves around Cady (Lindsay Lohan) who was raised in Africa, and home-schooled by her mother. When her family moves back into the United States she has to adjust to a new school, new friends, and a new personality. Through Cady's journey to fit in she encounters many great over the top characters, including the three popular girls nicknamed The Plastics. These 'Mean Girls" quotes are memorable, hilarious, and have a life of their own.

"That is so fetch!" by Gretchen. This "Mean Girls" quote is said more than once by Gretchen throughout the movie. Gretchen desperately tries to get the slang term fetch to catch on amongst the other mean girls, but ring leader Regina always shuts her mission down. Gretchen uses the word fetch to describe something cool, or hip. Every time Gretchen says fetch around Regina, she gets talked down to about how it is a ridiculous word to use.

"Hey, buddy, you're not pretending anymore. You're plastic. Cold, shiny, hard plastic." by Janis. Throughout the movie "Mean Girls" Janis and Damian refer to the popular girls as The Plastics. Cady was supposed to befriend The Plastics to tear the group apart, but she wound up getting in too deep. This "Mean Girls" quote comes while Cady is throwing a party in which all the popular kids are in attendance. Janis and Damia drive by, see the party, and confront Cady about why they were not invited. It eventually leads Janis to calling out Cady for becoming an actual plastic mean girl.

"On Wednesdays we wear pink!" by Karen. The dimwitted Karen played by actress Amanda Seyfried says this simple yet memorable "Mean Girls" quote to Cady. The Plastics welcome new student Cady into their circle on a trial basis. They tell Cady the rules she must abide by in order to stay in with The Plastics, which includes wearing pink on Wednesdays. This quote is hilarious because Cady does not own pink clothes, so when Wednesday rolls around she borrows and wears Damian's large pink polo.

"My apologies. I have a nephew named Anfernee, and I know how mad he gets when I call him Anthony. Almost as mad as I get when I think about the fact that my sister named him Anfernee." by Mr. Duvall. This "Mean Girls" quote is Mr. Duvall's response after Cady tells him her name is pronounced exactly like the name Katie. Portrayed by Tim Meadows, Mr. Duvall is one of the teachers at Cady's new school, and on her first day he pronounces her name exactly as it is spelled. Mr. Duvall may not be shown a lot throughout the movie, but when he is, he always has a hilarious one-liner.

"If you're from Africa, why are you white?" by Karen. When Cady informs the popular girls she used to live in Africa, Karen questions why she is white. Mean girl Gretchen quickly tells Karen she cannot ask people why they are white, which adds more humor to the quote. Amanda Seyfried portrays the air-head Karen perfectly, and you actually believe she thinks only African Americans live in Africa. This "Mean Girls" quote shows how the not-so-bright Karen has no filter, and says whatever pops into her brain.